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Biblioteca(s): | INIA Las Brujas.
Fecha corriente: | 29/04/2015
Fecha de la última actualización: | 15/10/2019
Autoria: | GRASSO, A.; GOLDBERG, V.; NAVAJAS, E.; IRIARTE, W.; GIMENO, D.; AGUILAR, I.; MEDRANO, J.F.; RINCÓN, G.; CIAPPESONI, G.
Afiliación: | ANDRES NICOLAS GRASSO PALAS, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; VIRGINIA GOLDBERG BIANCHI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ELLY ANA NAVAJAS VALENTINI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; WANDA IRIARTE GRECO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; DIEGO GIMENO, SUL (Secretariado Uruguayo de la Lana).; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JUAN F. MEDRANO, Universidad de California Davis (UCD); GONZALO RINCÓN, Universidad de California Davis (UCD); CARLOS GABRIEL CIAPPESONI SCARONE, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay.
Título: | Genomic variation and population structure detected by single nucleotide polymorphism arrays in Corriedale, Merino and Creole sheep.
Año de publicación: | 2014
Fuente/Imprenta: | Genetics and Molecular Biology, 2014, v.37, n.2, p.389-395.
DOI: | 10.1590/S1415-47572014000300011
Idioma: | Inglés
Notas: | Article history: Received: August 29, 2013 / Accepted: March 16, 2014.

Contenido:

ABSTRACT.

The aim of this study was to investigate the genetic diversity within and among three breeds of sheep: Corriedale, Merino and Creole. Sheep from the three breeds (Merino n = 110, Corriedale n = 108 and Creole n = 10) were genotyped using the Illumina Ovine SNP50 beadchip®
. Genetic diversity was evaluated by comparing the minor allele frequency (MAF) among breeds. Population structure and genetic differentiation were assessed using STRUCTURE software, principal component analysis (PCA) and fixation index (FST). Fixed markers (MAF = 0) that were different
among breeds were identified as specific breed markers. Using a subset of 18,181 single nucleotide polymorphisms (SNPs), PCA and STUCTURE analysis were able to explain population stratification within breeds. Merino and Corriedale divergent lines showed high levels of polymorphism (89.4% and 86% of polymorphic SNPs, respectively) and moderate genetic differentiation (FST = 0.08) between them. In contrast, Creole had only 69% polymorphic SNPs and 
showed greater genetic differentiation from the other two breeds (FST = 0.17 for both breeds). Hence, a subset of molecular markers present in the OvineSNP50 is informative enough for breed assignment and population structure analysis of commercial and Creole breeds.

Palabras-Clave: | OVINE SNP50.
Thesagro: | DIVERSIDAD GENETICA; OVEJA; OVINOS; RAZAS (ANIMALES).
Categoría del tema: | L10 Genética y mejoramiento animal

URL:

http://www.ainfo.inia.uy/digital/bitstream/item/4414/1/Grasso-N.-2014.-Genetcs-and-Mol.Biol.v37n2.pdf
http://www.scielo.br/pdf/gmb/v37n2/a11v37n2.pdf

Registro original: | INIA Las Brujas (LB)
Ejemplares: | LB - (100358-1) - PXI - AP - DD - PP/GENETICS&MOL.BIOL./2014 -  -  - DIS