Fecha/hora: 13/06/2024 05:09:37

Biblioteca(s): 	INIA Las Brujas.	
Fecha corriente: 	10/08/2021	
Fecha de la última actualización: 	10/08/2021	
Autoria: 	MACHADO, M.; QUEIROZ C.R.R.; WILSON T.M.; SOUSA D.E.R.; CASTRO M.B.; SARAVIA, A.; LEE S.T.; ARMIEN A.G.; BARROS S.S.; RIET-CORREA, F.	
Afiliación: 	MIZAEL MACHADO DA COSTA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CINTIA R.R. QUEIROZ, Veterinary Pathology Laboratory, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.; TAIS M. WILSON, Veterinary Pathology Laboratory, Veterinary Teaching Hospital, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Via L4 Norte, Distrito Federal, Brasília, Brazil.; DAVI E.R. SOUSA, Veterinary Pathology Laboratory, Veterinary Teaching Hospital, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Via L4 Norte, Distrito Federal, Brasília, Brazil.; MÁRCIO B. CASTRO, Veterinary Pathology Laboratory, Veterinary Teaching Hospital, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Via L4 Norte, Distrito Federal, Brasília, Brazil.; ANDERSON SARAVIA DE MELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; STEPHEN T. LEE, Poisonous Plant Research Laboratory, Agriculture Research Service, United States Department of Agriculture, Logan, United States.; ANÍBAL G. ARMIÉN, California Animal Health & Food Safety Laboratory System (CAHFS), School of Veterinary Medicine, University of California, Davis, United States.; SEVERO S. BARROS, Veterinary Pathology Laboratory, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil.; FRANKLIN RIET-CORREA AMARAL, Graduate Program in Animal Science in the Tropics, Escola de Medicina Veterinária e Zootecnia, Universidade Federal da Bahia, Salvador, Bahia, Brazil.	
Título: 	Endemic Xanthium strumarium poisoning in cattle in flooded areas of the Araguari River, Minas Gerais, Brazil.	
Año de publicación: 	2021	
Fuente/Imprenta: 	Toxicon, 2021, volume 200, pages 23-29. Doi: https://doi.org/10.1016/j.toxicon.2021.06.019	
ISSN: 	0041-0101	
DOI: 	10.1016/j.toxicon.2021.06.019	
Idioma: 	Inglés	
Notas: 	Article history: Received 22 May 2021; Received in revised form 29 June 2021; Accepted 30 June 2021; Available online 2 July 2021.
Corresponding author: Riet-Correa, F.; Graduate Program in Animal Science in the Tropics, Escola de Medicina Veterinária e Zootecnia, Universidade Federal da Bahia, Salvador, Bahia, Brazil; email:franklinrietcorrea@gmail.com	
Contenido: 	ABSTRACT - In this paper, we describe poisoning outbreaks of Xanthium strumarium in cattle on the borders of the Araguari River, Southeastern Brazil. In this region, several hydroelectric plants promote transient flooding, which creates a favorable environment for the invasion of X. strumarium in extensive areas, often as the predominant species in those areas. The outbreaks occurred between July and September (dry season). Bovines of all ages were affected, including suckling animals. Mortality varied from 2% to 5.5%. The animals exhibited ataxia, weakness, loss of balance, recumbency, and the majority were found dead. Laboratory results showed a marked increase in the serum activities of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, and gamma-glutamyltransferase. Histological and ultrastructural changes in the liver consisted of centrilobular necrosis and hemorrhage. On toxicological evaluation, the dicotyledons contained 0.30 &#956;g/mg of atractyloside and 0.37 &#956;g/mg of carboxyatractyloside. Considerable economic loss has occurred in this region due to the lack of knowledge regarding X. strumarium as a toxic plant and its adaptation to the environmental and climatic conditions of the region, which have made the condition endemic. 
© 2021 Elsevier Ltd	
Palabras-Clave: 	Acute hepatotoxicosis; Carboxyatractyloside; Cattle; Hydroelectric plants; Toxic plants; Xanthium strumarium.	
Categoría del tema: 	L01 Ganadería	
Registro original: 	INIA Las Brujas (LB)	
Ejemplares: 	LB - (102810-1) - PXI - AP - DD - PP/TOXICON/2021 -  -  - DIS