Fecha/hora: 16/06/2024 09:58:00

Biblioteca(s): | INIA La Estanzuela.
Fecha corriente: | 29/07/2022
Fecha de la última actualización: | 31/08/2022
Autoria: | DORSCH, M.; FRANCIA, M.E.; TANA, L.R.; GONZÁLEZ, F.C.; CABRERA, A.; CALLEROS, L.; SANGUINETTI, M.; BARCELLOS, M.; ZARANTONELLI, L; CIUFFO, C.; MAYA, L.; CASTELLS, M.; MIRAZO, S.; SILVEIRA, C.S.; RABAZA, A.; CAFFARENA, D.; DONCEL, B.; ARÁOZ, V.; MATTO, C.; RMENDANO, J.I.; SALADA, S.; FRAGA, M.; FIERRO, S.; GIANNITTI, F.
Afiliación: | MATÍAS ANDRÉS DORSCH, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MARÍA E. FRANCIA, Laboratorio de Biología de Apicomplejos, Instituto Pasteur de Montevideo, Montevideo, Uruguay.; LEANDRO R. TANA, Laboratorio de Biología de Apicomplejos, Instituto Pasteur de Montevideo, Montevideo, Uruguay.; FABIANA C. GONZÁLEZ, Laboratorio de Biología de Apicomplejos, Instituto Pasteur de Montevideo, Montevideo, Uruguay.; ANDRÉS CABRERA, Laboratorio de Interacciones Hospedero-Patógeno, Instituto Pasteur de Montevideo, Montevideo, Uruguay.; LUCÍA CALLEROS, Sección de Genética Evolutiva, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.; MARGARITA SANGUINETTI, Sección de Genética Evolutiva, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.; MAILA BARCELLOS, Sección de Genética Evolutiva, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.; LETICIA ZARANTONELLI, Unidad Mixta Instituto Pasteur de Montevideo e Instituto Nacional de Investigación Agropecuaria (UMPI), Montevideo, Uruguay.; CAMILA CIUFFO, Unidad Mixta Instituto Pasteur de Montevideo e Instituto Nacional de Investigación Agropecuaria (UMPI), Montevideo, Uruguay.; LETICIA MAYA, Laboratorio de Virología Molecular, Departamento de Ciencias Biológicas, Centro Universitario Regional (CENUR) Litoral Norte, Universidad de la República, Salto, Uruguay.; MATÍAS CASTELLS, Laboratorio de Virología Molecular, Departamento de Ciencias Biológicas, Centro Universitario Regional (CENUR) Litoral Norte, Universidad de la República, Salto, Uruguay.; SANTIAGO MIRAZO, Laboratorio de Virología, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay.; CAROLINE DA SILVA SILVEIRA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANA VIRGINIA RABAZA MARTINEZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; RUBEN DARÍO CAFFARENA LEDESMA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay./Unidad Académica Salud de los Rumiantes, Departamento de Producción Animal, Facultad de Veterinaria, Universidad de la República, Montevideo, Uruguay.; BENJAMÍN DONCEL DÍAZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay./Laboratorio de Patología Veterinaria, Facultad de Medicina Veterinaria y de Zootecnia, Universidad Nacional de Colombia, Sede Bogotá, Bogotá, Colombia.; VIRGINIA 	ARÁOZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; CAROLINA MATTO, Laboratorio Regional Noroeste, División de Laboratorios Veterinarios (DILAVE) Miguel C. Rubino, Ministerio de Ganadería, Agricultura y Pesca (MGAP), Paysandú, Uruguay.; JOAQUÍN I. ARMENDANO, Facultad de Ciencias Veterinarias, Universidad Nacional del Centro de la Provincia de Buenos Aires (UNCPBA), Tandil, Argentina.; SOFÍA SALADA, Secretariado Uruguayo de la Lana (SUL), Montevideo, Uruguay.; MARTIN FRAGA COTELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; SERGIO FIERRO, Secretariado Uruguayo de la Lana (SUL), Montevideo, Uruguay.; FEDERICO GIANNITTI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay.
Título: | Diagnostic investigation of 100 cases of abortion in sheep in Uruguay: 2015-2021.
Año de publicación: | 2022
Fuente/Imprenta: | Frontiers in Veterinary Science, 2022; i. 9:904786. OPEN ACCESS. Doi: https://doi.org/10.3389/fvets.2022.904786.
DOI: | 10.3389/fvets.2022.904786
Idioma: | Inglés
Notas: | Article history: Received: 25 March 2022/Accepted: 13 April 2022/Published: 19 May 2022.
Contenido: | Abstract: The aim of this work was to identify causes of abortion through laboratory investigations in sheep flocks in Uruguay. One hundred cases of abortion, comprising 58 fetuses, 36 fetuses with their placentas, and 6 placentas were investigated in 2015?2021. Cases were subjected to gross and microscopic pathologic examinations, and microbiological and serological testing for the identification of causes of abortion, including protozoal, bacterial, and viral pathogens. An etiologic diagnosis was determined in 46 (46%) cases, including 33 (33%) cases caused by infectious pathogens, as determined by the detection of a pathogen along with the identification of fetoplacental lesions attributable to the detected pathogen. Twenty-seven cases (27%) were caused by Toxoplasma gondii, 5 (5%) by Campylobacter fetus subspecies fetus, and 1 (1%) by an unidentified species of Campylobacter. Fourteen cases (14%) had inflammatory and/or necrotizing fetoplacental lesions compatible with an infectious etiology. Although the cause for these lesions was not clearly identified, T. gondii was detected in 4 of these cases, opportunistic bacteria (Bacillus licheniformis, Streptococcus sp.) were isolated in 2 cases, and bovine viral diarrhea virus 1 subtype i (BVDV-1i) was detected in another. Campylobacter jejuni was identified in 1 (1%) severely autolyzed, mummified fetus. BVDV-2b was identified incidentally in one fetus with an etiologic diagnosis of toxoplasmosis. Microscopic agglutination test revealed antibodies against ?1 Leptospira serovars in 15/63 (23.8%) fetuses; however, Leptospira was not identified by a combination of qPCR, culture, fluorescent antibody testing nor immunohistochemistry. Neospora caninum, Chlamydia abortus, Chlamydia pecorum, Coxiella burnetii and border disease virus were not detected in any of the analyzed cases. Death was attributed to dystocia in 13 (13%) fetuses delivered by 8 sheep, mostly from one highly prolific flock. Congenital malformations including inferior prognathism, a focal hepatic cyst, and enterohepatic agenesis were identified in one fetus each, the latter being the only one considered incompatible with postnatal life. Toxoplasmosis, campylobacteriosis and dystocia were the main identified causes of fetal losses. Despite the relatively low overall success rate in establishing an etiologic diagnosis, a systematic laboratory workup in cases of abortion is of value to identify their causes and enables zoonotic pathogens surveillance.
Palabras-Clave: | ABORTION; CAMPYLOBACTEROSIS; DYSTOCIA; INFECTIOUS DISEASES; PATHOLOGY; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL; REPRODUCTIVE LOSSES; SHEEP; TOXOPLASMOSIS.
Thesagro: | ENFERMEDADES DE LOS ANIMALES; OVEJAS.
Categoría del tema: | L74 Trastornos misceláneos de los animales
URL: | http://www.ainfo.inia.uy/digital/bitstream/item/16635/1/fvets-09-904786.pdf
Registro original: | INIA La Estanzuela (LE)
Ejemplares: | LE - (103605-1) - PXI - AP - DD - PP/Frontiers in Veterinary Science/2022 -  -  - DIS